Directory

Myricx Bio

StartupBiotech & Life SciencesBritish

Biotech spinout from Imperial College London and the Francis Crick Institute developing a first-in-class class of antibody-drug conjugate payloads based on N-myristoyltransferase (NMT) inhibitors to treat cancer, with lead programmes targeting B7-H3 and HER2.

Napier AI

ScaleupFinanceAIBritish

AI-powered anti-financial-crime and AML compliance platform serving banks, payments firms and asset managers; trusted by over 100 institutions globally including HSBC and Starling Bank. Received a majority growth investment from Marlin Equity Partners in February 2025.

Newable

Ecosystem Bodies, Catapults & InstitutionsOtherAIIncubator / AcceleratorBritish

Newable is a London-based, employee-owned business support organisation founded in 1982 (originally as Greater London Enterprise, rebranded in 2016) that helps UK SMEs grow through finance, professional services, and workspace solutions. Its investment arm, Newable Private Investing (formerly London Business Angels), connects a network of over 500 angel investors with early-stage businesses in sectors including AI, medtech, robotics, fintech, and deep technology. The group employs approximately 1,200 people and supports over 43,000 SMEs annually.

NorthEdge

PESaaSOtherBritish

NorthEdge Capital is a regional private equity firm headquartered in Manchester with additional offices in Birmingham and Leeds, managing over £1 billion in funds across five funds. Founded in 2009, the firm focuses on lower mid-market buyout and development capital transactions across the technology, healthcare, and business services sectors in the North of England and Midlands. It has backed over 48 businesses and employs around 7,600 people across its portfolio.

Notion Capital

VCSaaSAIBritish

Notion Capital is Europe's leading early-stage business software investor, focusing exclusively on B2B SaaS, cloud services, and AI-driven software companies with global ambition. Founded in 2009 and based in London, the firm manages over $1 billion in AUM and has invested in more than 200 companies, including GoCardless and Tradeshift. It leads investments at an early stage and partners with founders throughout the journey from $1 million to $100 million in revenue.

Notpla

ScaleupClimateBritish

Sustainable packaging maker using seaweed and plants to create plastic-free, home-compostable films, coatings, sachets and rigid packaging.

Novalpina Capital

PEOtherBritish

Novalpina Capital is an independent European mid-market private equity firm founded in 2017 in London, focusing on control equity investments in companies with enterprise values of €200 million to €1 billion across the Benelux, DACH, France, Italy, and United Kingdom regions. The founding partners were removed from fund management by the firm's limited partners in 2021, with control transferred to a third-party manager, and the firm is no longer actively managed by its founders. The website remains live and the entity manages over €1 billion in total fund commitments.

Nscale

ScaleupAIBritish

Vertically integrated AI infrastructure provider operating data centres, GPU compute clusters and cloud orchestration for large-scale AI workloads; spun out of Arkon Energy in 2023 and backed by Aker, Nvidia and Microsoft.

Numan

ScaleupBiotech & Life SciencesConsumerBritish

Online men's health and preventive care platform offering diagnostics, GLP-1 weight management, testosterone replacement, hair loss and erectile dysfunction treatment via at-home testing and clinicians.

OLIO

ScaleupConsumerClimateBritish

Community sharing app enabling neighbours and local businesses to give away surplus food and unwanted household items for free, diverting them from landfill. Operates globally with millions of users and works with major retailers and food-service businesses on surplus redistribution.

OLIX Computing

ScaleupAIBritish

Photonic AI inference chip company developing an Optical Tensor Processing Unit (OTPU) that integrates SRAM with photonics, bypassing high-bandwidth memory to deliver GPU-competitive economics at lower cost. Raised $220 million in 2026, achieving unicorn status, with first customer shipments planned for 2027.

ORCA Computing

ScaleupQuantumBritish

Full-stack photonic quantum computing company building room-temperature, scalable photonic quantum systems. Deployed the first photonic quantum system at the UK National Quantum Computing Centre (NQCC) and develops hardware for both standalone and hybrid classical-quantum deployments.

ORE Catapult

Ecosystem Bodies, Catapults & InstitutionsClimateBritish

The Offshore Renewable Energy Catapult (ORE Catapult) is the UK's leading technology innovation and research centre for offshore renewable energy, established in 2013 by Innovate UK. It accelerates the creation and growth of UK companies in offshore wind, wave, and tidal energy, operating eight locations across the UK including the National Renewable Energy Centre in Blyth. The organisation employs over 300 people and collaborates with industry, government, and academia.

Octopus Electric Vehicles

ScaleupClimateBritish

UK's largest EV-only leasing company, offering salary-sacrifice EV schemes for businesses alongside home and public charging solutions and green energy tariffs. Funds over 27,000 cars and is expanding into fleet electrification services.

Omnea

ScaleupSaaSAIBritish

AI-native procurement orchestration platform for enterprise finance teams, centralising supplier onboarding, risk assessment, and spend management. Has raised over $138 million including a $50 million Series B in 2025, grown to 160+ employees, and was selected for Tech Nation's Future Fifty programme in 2026.

One Peak

VCSaaSFinanceBritish

London-based growth equity firm investing in B2B software and tech scaleups from expansion stage through to IPO or exit.

Onward

Ecosystem Bodies, Catapults & InstitutionsOtherBritish

Onward is the UK's leading centre-right think tank based in Westminster that develops bold and practical ideas to boost economic opportunity, build national resilience, and strengthen communities. It runs three research programmes covering the economy, the state, and social policy, and works closely with policymakers and businesses across the UK.

Open Rights Group

Ecosystem Bodies, Catapults & InstitutionsOtherBritish

Open Rights Group (ORG) is the UK's largest grassroots digital rights campaigning organisation, founded in 2005. It campaigns, lobbies, and pursues legal action to defend privacy and free speech online, tackling issues such as mass surveillance, internet censorship, and AI governance.

OpenWeather

ScaleupSpaceSaaSBritish

Weather and environmental data/forecasting platform aggregating satellite, radar, global models and 80,000+ stations via APIs (8M+ users; 2B+ forecasts/day); satellite remote-sensing data layer.

Orbital

ScaleupAIProptechForeign

AI platform for real estate law that automates property due diligence, title review and document-heavy legal workflows across the US and UK. Raised a $60 million Series B in January 2026 and supports more than 200,000 real estate transactions annually. Formerly known as Orbital Witness.

Orbital Industries

ScaleupAIOtherBritish

Uses frontier AI and simulation to discover and engineer advanced materials for industrial applications, starting with high-density cooling solutions for GPU data centres. Formerly known as Orbital Materials; completed a rebrand to Orbital Industries and raised a $50 million Series B in May 2026.

Ori Biotech

ScaleupBiotech & Life SciencesBritish

Biomanufacturing technology company offering a full-stack closed and automated platform (the IRO system) to standardise and scale cell and gene therapy manufacturing. The IRO platform received FDA Advanced Manufacturing Technology designation in September 2025, one of the first technologies to do so.

Oviva

ScaleupBiotech & Life SciencesConsumerForeign

Digital health platform delivering app-based treatment for diabetes, obesity, and diet-related conditions, with programmes commissioned by the NHS and private insurers across the UK and Europe.

Oxford Capital

VCFinanceAIBritish

Oxford-based venture capital firm investing over £500m into 100+ early-stage UK technology and science companies since 1999.