Directory

Sable Bio

StartupBiotech & Life SciencesAIBritish

AI-powered drug-safety platform providing predictive target and compound safety insights to reduce clinical-trial failure risk.

Samphire Neuroscience

StartupBiotech & Life SciencesBritish

Women's-health neurotech company behind Nettle, a CE-certified tDCS headband that eases menstrual pain, mood swings and brain fog without drugs.

Sania Therapeutics

StartupBiotech & Life SciencesBritish

Develops AAV gene therapies targeting specific neural circuits using tuneable, conditionally-activated ion channels.

Sano Genetics

StartupBiotech & Life SciencesAIBritish

UK precision medicine startup (founded 2017, $29M raised) that provides an end-to-end platform for clinical trials covering patient recruitment, at-home DNA testing, medical record retrieval, and long-term participant engagement.

Scale Space

CoworkingAIIncubator / AcceleratorBritish

Scale Space is a 200,000 sq ft innovation hub and co-working campus in White City, London, established as a joint venture between Imperial College London and Blenheim Chalcot in 2018. It supports over 100 innovative digital technology and life sciences businesses, offering flexible offices, co-working labs, and a growth network connecting members with venture builders, academics, and corporate innovators. The hub, which opened its first phase in 2020, is a central anchor of the White City Innovation District and also operates I-HUB and a Nottingham campus.

Scan.com

ScaleupBiotech & Life SciencesConsumerBritish

Medical imaging marketplace giving patients direct self-pay access to MRI, CT, ultrasound and X-ray scans across a network of imaging centres.

Scindo

StartupBiotech & Life SciencesAIBritish

AI-driven enzyme discovery platform that turns feedstocks — including waste plastics — into speciality ingredients historically derived from petrochemicals.

Scope

StartupAISaaSBritish

London AI workflow platform for the testing, inspection and certification (TIC) industry, automating field inspections and report generation for heavy asset operators.

Seabound

StartupClimateBritish

Develops onboard carbon capture devices that trap CO2 from ships' exhaust gases and convert it into limestone pebbles for offloading at port, targeting net-positive maritime decarbonisation.

Seapoint

StartupFinanceAIForeign

AI-native financial operations platform for early-stage startups, offering business accounts, multi-currency payments, cards, treasury, payroll, expenses, invoicing and FX in a single hub. Founded by ex-Stripe alumni and backed by €7.5m seed funding, Seapoint operates across the UK and Ireland.

Seed Haus

Incubator / AcceleratorOtherVCBritish

Seed Haus is a non-profit pre-seed technology accelerator and investor founded in 2017 and based in Edinburgh, Scotland, focused on backing early-stage startups across Scotland's startup ecosystem. The programme provides pre-seed investment of approximately £18,000 in exchange for 8% equity, alongside mentorship, infrastructure support, and assistance with customer acquisition, marketing, and distribution. It is among Scotland's most selective tech accelerators, having attracted backing from prominent Scottish entrepreneurs and investors.

Self Space

StartupBiotech & Life SciencesBritish

On-demand mental health service offering walk-in and virtual therapy on the high street, positioning everyday mental health care as routine maintenance rather than crisis response. Operates physical clinic locations across London alongside digital appointments.

Sen

ScaleupSpaceMediaBritish

London-based space media company providing the world's first continuous 4K livestream of Earth from orbit, with cameras on the International Space Station and a roadmap to a 100-satellite constellation. Distributes streams via its own platform, mobile apps and broadcast partners including ITVX.

Seneca Partners

VCOtherSaaSPEBritish

Seneca Partners is an award-winning specialist SME investment business based in Haydock, North West England, founded in 2010. The firm deploys growth capital into SMEs through tax-advantaged vehicles including Venture Capital Trusts (VCTs) and Enterprise Investment Schemes (EIS), having invested over £130 million into more than 100 companies.

Sequence

ScaleupFinanceAIBritish

AI agent platform that automates billing, invoicing and revenue operations for B2B finance teams, with real-time revenue recognition and support for complex pricing models.

Serendipity Capital

VCAICybersecurityForeign

Serendipity Capital is a Singapore-founded global investment firm focused on B2B, dual-use technologies at the intersection of commercial value and national security, established in 2019. The firm operates as a permanent capital vehicle investing in early-stage to growth companies across quantum technologies, artificial intelligence, semiconductors, space, autonomous systems, and cybersecurity, with offices in Singapore, Boston, and London.

SheMed

ScaleupBiotech & Life SciencesConsumerBritish

Personalised women's healthcare and GLP-1 weight management platform offering blood-test screening, tailored treatment plans, and physician-prescribed medication.

Sixth Element Capital

VCOtherBritish

Sixth Element Capital (6EC) is a specialist UK venture capital fund manager focused exclusively on oncology. It manages the £70 million CRT Pioneer Fund, a dedicated oncology investment fund established in 2012 to bridge the gap between cancer drug discovery and early clinical development in Europe.

Skin Analytics

ScaleupBiotech & Life SciencesAIBritish

Developer of DERM, an autonomous AI medical device for skin cancer detection (CE Class III / UKCA Class IIa), deployed across NHS dermatology pathways.

Skyports

ScaleupLogisticsBritish

Builds and operates vertiports and runs autonomous drone-delivery and inspection services for advanced air mobility, combining eVTOL infrastructure development with commercial drone operations.

Skyral

ScaleupDefenceAIBritish

Modelling and simulation / synthetic-environment platform combining digital-twin modelling with AI; serves UK MOD, NATO, Raytheon, and Microsoft.

SmartestEnergy

ScaleupClimateBritish

Independent B2B energy supplier and trader that buys, sells and trades renewable power for businesses and independent generators.

Smedvig Ventures

VCSaaSAIBritish

London-based VC arm of the Smedvig family office, investing €4-8m in B2B tech companies across Europe from early traction to scale.

Social Tech Trust

GrantmakerOtherIncubator / AcceleratorBritish

Social Tech Trust (formerly Nominet Trust) is an independent UK charity and the country's leading dedicated grant-maker in socially motivated technology. Founded in 2008 as the corporate foundation of Nominet, it has provided over £31 million in funding to more than 750 technology-for-good initiatives across the UK, with a focus on inclusion, healthcare, and equitable access; it also operates Social Tech Ventures, a flexible impact investment fund for aligned ventures.