Directory

OTIF Ventures

VCAIOtherBritish

Oxford Investment Consultants LLP, trading as OTIF Ventures, is a venture capital firm established in 2015 that backs early-stage, EIS-eligible university spinout companies from leading UK research institutions, particularly Oxford and Cambridge, across Life Sciences, Deep Tech, and Physical Sciences. The firm provides EIS-eligible funding alongside board representation and strategic support, and has made investments in over 38 companies including notable exits such as Oxitec and OrganOx.

Oato

StartupConsumerBritish

Fresh British oat-drink brand made from UK-grown oats, delivered in reusable glass bottles via milk rounds and sold through major retail listings.

Occam Industries

StartupDefenceBritish

Software-only autonomy for unmanned and autonomous machines, enabling low-cost drones and robots to operate independently of GPS and communications links — resilient to jamming and signal loss. Raised a €3 million pre-seed round in 2026 and has completed field testing with the Ukrainian DefenceTech cluster Brave1.

Oddbox

ScaleupClimateConsumerBritish

B Corp subscription-delivery service rescuing surplus and cosmetically imperfect fruit and vegetables directly from farms across the UK and Europe, reducing food waste at source. Delivers customisable weekly boxes to homes across England.

Odin

StartupFinanceSaaSFunding PlatformBritish

Odin is a UK fintech platform that enables angel investors, fund managers, and founders to launch and run investment vehicles entirely online. The platform handles SPV creation, investor onboarding, KYC/AML, banking, legal structuring, and post-close administration, and administers over $500 million in assets across pre-seed to pre-IPO investments. Founded in 2019, Odin operates as an Authorised Representative of Talbot Capital Limited, regulated by the FCA.

Offset Labs

StartupDefenceAIBritish

UK-Ukrainian AI lab for defence and national security, building frontier AI models for signal and voice processing in operational environments. Formerly known as Byne; raised a €600,000 pre-seed round in 2025 led by Archangel Ventures with participation from Amadeus Capital Partners.

Old College Capital

VCAIFinanceAcademiaBritish

Old College Capital is the University of Edinburgh's in-house venture investment fund, supporting early-stage spinouts and startups associated with the University. The fund co-invests alongside experienced private-sector partners from pre-seed through to Series A, focusing on sectors including biotechnology, AI, energy, data, robotics, and fintech. Since its founding in 2012, it has committed over £15 million across more than 100 investments, leveraging approximately £100 million in co-investment from partners.

Olombria

StartupOtherBritish

Precision agtech company using native hoverflies, habitat design, and environmental monitoring tools to boost crop pollination and yields for farmers. Originated from the Royal College of Art and was previously known as FlyPollination.

One Nucleus

Ecosystem Bodies, Catapults & InstitutionsOtherBritish

One Nucleus is a not-for-profit life sciences and healthcare membership organisation supporting institutions, companies, and individuals across the UK's Cambridge–London life sciences cluster, with approximately 470 members including pharmaceutical, biotech, medical device, and diagnostic companies. It was formed in 2010 through the merger of Cambridge-based ERBI (established 1997) and the London Biotechnology Network, and provides connectivity, networking events, training, and member services.

OneBalance

ScaleupFinanceBritish

Crypto software firm building chain/gas abstraction and a cross-chain account framework (Toolkit) so developers can offer instant cross-chain trading, payments and yield via API.

OneID

ScaleupFinanceBritish

Bank-verified, real-time digital identity verification service for onboarding, fraud reduction, age and ID verification, using data from UK banks (e.g. NatWest).

Online Oceans

StartupDefenceBritish

Solar-powered autonomous surface vessels (Scout) plus Tether C2 platform for anti-submarine warfare, subsea protection and maritime border security.

Open Climate Fix

Ecosystem Bodies, Catapults & InstitutionsClimateAIBritish

Non-profit AI product lab building open-source solar generation and cloud-movement forecasting models to improve grid reliability and cut emissions.

OpenUK

Ecosystem Bodies, Catapults & InstitutionsOtherBritish

OpenUK is the UK body for the business of open technology, convening business, academia and technologists across open-source software, open-source hardware, open data and open standards. It operates as a not-for-profit company limited by guarantee and runs the annual State of Open Con conference. The organisation advocates for UK leadership in open technology through its Community, Legal & Policy, and Learning pillars.

Opna

StartupClimateBritish

Climate finance platform enabling corporates to discover, finance, monitor and manage pre-assessed carbon removal and reduction projects to reach net zero.

Opteran

ScaleupAIBritish

'Natural Intelligence' autonomy chips and software reverse-engineered from insect neural circuits, enabling low-power on-edge perception, navigation and decision-making for robots and autonomous machines.

Opto Health

StartupBiotech & Life SciencesConsumerBritish

Digital triage platform that directs patients to the appropriate level of urgent and emergency care via symptom assessment. An MHRA-registered UKCA Class I medical device, it covers 400+ conditions in multiple languages and integrates with NHS Spine and Trust clinical systems.

OrbiSky Systems

StartupSpaceAIBritish

Space assurance company building mission evidence infrastructure for autonomous in-orbit manufacturing, ISAM operations, hosted payload verification and anomaly-aware telemetry review. Awarded a UK Space Agency contract in 2026 to define end-to-end payload verification for in-orbit manufacturing.

Oriole Networks

ScaleupAIClimateBritish

UCL spin-out using photonics to connect AI chips with light, enabling large language models to be trained up to 100x faster while consuming a fraction of the power of conventional data-centre interconnects.

OutThink

ScaleupCybersecurityAIBritish

AI human risk management platform that predicts and prevents human-initiated security incidents.

Outward VC

VCFinanceProptechBritish

Outward VC is a London-based early-stage venture capital firm investing in founders solving important problems at the intersection of financial services and society. The firm backs companies across fintech and adjacent sectors including insurtech, proptech, healthtech, edtech, and legaltech, with a people-first investment philosophy.

Ovo Labs

StartupBiotech & Life SciencesForeign

Fertility technology company developing treatments to improve IVF success rates, focused on egg quality and chromosomal errors in women over 35.

OxAngels

VCOtherBritish

OxAngels is an angel investment group comprising individuals with a connection to the University of Oxford who are passionate about supporting early-stage and start-up companies to create social and economic value through innovation and entrepreneurship.

Oxford Seed Fund

VCOtherAIAcademiaBritish

Oxford Seed Fund is Europe's largest student- and alumni-managed venture fund, housed within Saïd Business School's Entrepreneurship Centre at the University of Oxford. It invests up to £100,000 into early-stage, technology-enabled startups where an Oxford student, alumnus, or member of academic staff is part of the founding team, and provides access to the wider Oxford network. Since its first fund in 2013, it has backed over 23 companies in that fund cycle, including two unicorns — Onfido and Go1 — with the second fund now active.